Parkinson’s disease is a nervous system coordination condition, which gets worse over time. Cerebral paralysis, ataxia and Tourette’s disease are other movement disorders. More than 6 million people worldwide have Parkinson’s disease, according to the World Health Organization.

 

What is Parkinson’s disease

The signs of Parkinson’s disease grow progressively. Sometimes they begin with a little tremor in one hand and a sense of stiffness in the body. With time, there are other signs and dementia in some individuals. Poor levels of dopamine in the brain are the main cause of the effects.

In a 2015 French study, men are 50% more likely than women than men to suffer from Parkinson’s disease in general but the risk for women seems to grow at age. In addition, women are at risk.

Many adults 60 or older experience symptoms. However, it occurs earlier in 5-10% of cases. The “early development” of Parkinson’s disease is named as it occurs before the age of 50 years.

 

Early signs

Here are some of the early signs of Parkinson’s:

  1. Movement: There may be tremors in the hands.
  2. Coordination: A lower sense of coordination and equilibrium will lead people to drop objects.
  3. Way to walk: the way people walk can be changed to lean slightly forward as if they were hurried. The patient will even go wrong.
  4. Facial expression: can become rigid as a result of changes in face muscle nerves.
  5. The voice: the voice can be shivered or the person can talk louder than before.
  6. Handwriting: It can be harder to write.
  7. Smell sensation: Smell loss may be the early warning.
  8. Sleep problems: This is a feature of Parkinson’s disease, and it may be an early sign. Restless legs may contribute to this.

 

Other common symptoms include:

  1. Mood changes, including depression
  2. Difficulty chewing and swallowing
  3. Urination problems
  4. Constipation

REM sleep disorder: The authors of a study published in 2015 describe another neurological condition, REM sleep disorder, as a “strong predictor” of Parkinson’s disease and some other neurological condition.

 

The importance of recognizing early symptoms

Many people believe that the early signs of Parkinson’s disease are natural signs of aging. For this reason, they may not seek help.

However, treatment is likely to be more effective if a person takes it early in preventing the progression of Parkinson’s disease. For this reason, it is important to get an early diagnosis if possible. If treatment is not started until a person has clear symptoms, it will not be as effective. Moreover, a number of other conditions can have similar symptoms. These include:

  1. Parkinson’s disease caused by drugs
  2. Head trauma
  3. Encephalitis
  4. Stroke

Similarities with other conditions can make it difficult for doctors to diagnose Parkinson’s disease in its early stages. Movement symptoms may begin on one side of the body and gradually affect both sides.

 

The Reasons

Some brain nerve cells rapidly degenerate or die in Parkinson’s disease. A lack of neurons producing a chemical messenger in the brain called dopamine results in many of the effects. If dopamine concentrations decrease, excessive brain function leads to decreased mobility and other Parkinson’s symptoms. The cause of Parkinson’s disease is unknown, but several factors seem to play a role, including:

 

Genes

Relevant gene mutation has been identified, causing Parkinson’s disease. But those signs are unlikely, unless there are rare cases of Parkinson’s disease in several family members. Any genetic differences seem therefore to raise the likelihood of developing Parkinson’s disease, albeit with a comparatively limited risk that one of these genetic markers can develop Parkinson’s disease.

Environmental stimuli

Exposure to certain toxins or environmental factors may increase the risk of developing Parkinson’s disease at a later time, but the risk is relatively small. The researchers also note that many changes occur in the brains of people with Parkinson’s disease, although it is not clear why these changes occur. These changes include:

 

Presence of Lewy bodies: clumps of certain substances within brain cells are microscopic markers of this disease. These are called Lewy bodies, and researchers believe these Lewy bodies hold important evidence for the cause of this disease.

Alpha-synuclein is found inside Lewy bodies. Although many substances are present within Lewy bodies, scientists believe that the most important of them is the widespread natural protein called alpha-synuclein (A-Synuclein). It is found in all Lewy bodies in an agglomerated form that cells cannot degrade. This is an important focus currently among researchers in this disease.

 

Risk factors

This disease risk factors include:

Genetics: The possibility of contracting the condition is increased by being closely related to Parkinson’s disease. Your stakes remain limited, though, unless you have several relatives with this disease in your family.

Gender: Male Parkinson’s disease is more likely than female.

Age: The Parkinson disease is rarely found in young adults. It normally begins at mid- to late age, and with age the risk increases. Individuals normally inherit the illness at 60 or older.

Toxin exposure: The risk of contracting Parkinson’s disease can be slightly increased by ongoing exposure to herbicides and pesticides.

 

Complications

Parkinson’s disease often accompanies these additional treatable problems:

  1. Depression and changing emotions: Even in the very early stages you can become depressed. The treatment of depression will facilitate the management of other challenges of this disease.
  2. Other emotional improvements, such as panic, anxiety or confidence loss can also be experienced. Doctors can cure these effects by giving you medicines.
  3. Thinking trouble: you may have memory disorders (dementia) and trouble thinking. This normally happens in the latter stages of PD. Cognitive disorders such as these are not very responsive to drugs.
  4. Bladder problems: Parkinson’s disease may cause bladder problems, including an inability to control urine or difficulty urinating.
  5. Constipation: Many people with this disease become constipated, mainly due to the slowdown of the digestive system.
  6. Swallowing problems: You may experience difficulties swallowing as your condition progresses. Saliva may build up in your mouth due to slowed swallowing, leading to drooling.
  7. Problems with chewing and eating: this disease affects the muscles in the mouth in the late stages, which makes chewing difficult. This could lead to choking and malnutrition.

 

You may also experience:

  1. Changes in blood pressure
  2. Impaired sense of smell
  3. Fatigue
  4. Pain in certain areas of the body
  5. Impotence

 

Prevention

It is unable to avoid this disease, but evidence has demonstrated that such lifelong practices will help reduce the risks.

Turmeric: This spice contains an antioxidant agent called curcumin. At least one experimental study has shown it can help to discourage this disease from causing protein clumping.

The use of a certain form of antioxidant – flavonoids – can, according to reports, decrease the risk of developing this disease. In bananas, onions, some fruits, tea, and red grapes, flavonoids are included.

Avoid reused cooking oils: Scientists have combined poisonous compounds called aldehydes, Alzheimer’s disease and other neurodegenerative disorders with certain kinds of cancer. Avoid reheated cooking oils. Heating and then again using such oils such as sunflower oil will result in the presence of aldehydes in certain oils.

 

Avoiding Toxins: The risks of neurodegenerative conditions like Parkinson’s disease may be increased by exposure to herbicides, pesticides or other toxins. People should take care, for example by using protective equipment, when using certain materials.